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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF9
All Species:
6.97
Human Site:
T118
Identified Species:
13.94
UniProt:
O60383
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60383
NP_005251.1
454
51444
T118
Y
N
T
V
R
L
F
T
P
C
T
R
H
K
Q
Chimpanzee
Pan troglodytes
XP_527008
455
51476
T118
Y
N
T
V
R
L
F
T
P
C
T
R
H
K
Q
Rhesus Macaque
Macaca mulatta
XP_001101902
271
31418
Dog
Lupus familis
XP_549005
393
44984
G63
Q
R
K
P
Q
V
L
G
H
P
L
R
Y
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q07105
441
49630
E100
Y
K
T
Y
A
T
K
E
G
V
P
K
P
S
R
Rat
Rattus norvegicus
P49001
393
44364
Q63
L
S
M
F
G
L
K
Q
R
P
T
P
S
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510645
359
41050
A29
G
M
N
P
Q
S
L
A
A
A
S
E
L
S
F
Chicken
Gallus gallus
Q90752
405
46039
S75
L
R
R
R
P
Q
P
S
K
S
A
V
I
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P85857
404
46271
Y74
D
P
V
V
P
H
D
Y
M
I
S
I
Y
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
P220
K
D
K
L
K
P
D
P
S
T
L
V
E
I
E
Honey Bee
Apis mellifera
XP_001122815
374
42068
T43
H
L
H
L
H
S
D
T
A
K
H
F
A
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
M65
W
D
L
Y
R
Q
Q
M
A
A
T
E
G
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50
28.6
N.A.
72
21.5
N.A.
26.4
21.8
N.A.
21.1
N.A.
21.7
21.3
N.A.
20.2
Protein Similarity:
100
99.1
54.1
45.1
N.A.
80.6
39.2
N.A.
44.2
38.3
N.A.
39.6
N.A.
36.9
40.3
N.A.
39.4
P-Site Identity:
100
100
0
6.6
N.A.
13.3
20
N.A.
0
0
N.A.
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
0
26.6
N.A.
26.6
26.6
N.A.
13.3
6.6
N.A.
26.6
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
9
25
17
9
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% C
% Asp:
9
17
0
0
0
0
25
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
17
9
0
9
% E
% Phe:
0
0
0
9
0
0
17
0
0
0
0
9
0
0
9
% F
% Gly:
9
0
0
0
9
0
0
9
9
0
0
0
9
0
9
% G
% His:
9
0
9
0
9
9
0
0
9
0
9
0
17
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
9
9
17
0
% I
% Lys:
9
9
17
0
9
0
17
0
9
9
0
9
0
25
0
% K
% Leu:
17
9
9
17
0
25
17
0
0
0
17
0
9
0
9
% L
% Met:
0
9
9
0
0
0
0
9
9
0
0
0
0
9
0
% M
% Asn:
0
17
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
17
17
9
9
9
17
17
9
9
9
9
0
% P
% Gln:
9
0
0
0
17
17
9
9
0
0
0
0
0
0
17
% Q
% Arg:
0
17
9
9
25
0
0
0
9
0
0
25
0
9
9
% R
% Ser:
0
9
0
0
0
17
0
9
9
9
17
0
9
17
9
% S
% Thr:
0
0
25
0
0
9
0
25
0
9
34
0
0
0
9
% T
% Val:
0
0
9
25
0
9
0
0
0
9
0
17
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
0
17
0
0
0
9
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _